What is the challenge EASYGEN addresses?

Only 18% of patients have access to CAR-T therapy. About 30% of total cost-of-care are related to logistics and bridging therapy. Cell therapies often travel across borders twice under tight customs and shipping constraints. Manufacturing depends on manual, error-prone processes with cleanroom-trained technicians. Treatment costs reach over €500,000 per patient, making it unaffordable for many health systems to scale up access.

EASYGEN: Advancing CAR-T Cell Therapy for cancer in Europe

Q: What is EASYGEN's mission?

EASYGEN's goal is to enable an automated, modular manufacturing platform for CAR-T cell production at the point-of-care. The project aims to reduce treatment cost by 50%, reduce manufacturing time significantly, broaden eligibility for new European patient groups, and embed a platform seamlessly into routine hospital workflows.

Paving the way to faster, more accessible immunotherapies

EASYGEN is a collaborative EU project aiming to optimise hospital workflows of CAR-T cell therapy for a sustainable healthcare workforce.

EASYGEN Illustration of a CAR-T cell engaging with a cancer cell, representing targeted immunotherapy.

The challenge

Today’s licensed CAR-T therapies are typically manufactured in central GMP plants. In real-world cohorts, the median vein-to-vein time ranges between 4 and 6 weeks.

Locke FL 2025 Blood Adv.

Only 18%

of eligible diffuse large B-cell lymphoma (DLBCL) patients in Europe receive CAR-T therapy

IQVIA Institute 2025

`About 30%`

of the total cost-of-care are related to logistics and bridging therapy (- by decentralization the longest and most expensive part will be removed)

Silvola S 2022 Value Health

Cross-border complexity

Cell therapies often travel across borders twice, under tight customs and shipping constraints.

Manual, error-prone processes

Manufacturing still depends on cleanroom-trained technicians and high-touch workflows which can result in delays and errors.

Unaffordable treatment costs

With treatment costs reaching over €500,000 per patient, many health systems can’t afford to scale up access. Every day lost can mean a life lost.

Senior K 2025 Lancet

Our mission

EASYGEN's (EASY workflow integration for GENe therapy) mission is to develop scalable, automated and hospital-based manufacturing solutions that bring CAR-T production closer to the patient and enable the global democratization of access to advanced cell therapies.

Reduce treatment cost by 50%

Reduce manufacturing time significantly

Broaden eligibility for new European patient groups

Embed a platform seamlessly into routine hospital workflows

EASYGEN introduction video

Triangle behind a mountain range made with structural grid like texture

Latest news

A major milestone as the EASYGEN consortium kicks off

EASYGEN consortium kicks off: Decentralized, automated CAR-T manufacturing moves into the hospital.

Read article

Ring that bell

Inspired by the first CAR-T survivor, Mags McCarthy and Bruce Levine created Ring That Bell, a tribute to patients.

Read post

EASYGEN partners

EASYGEN brings together 18 international partners from academia and industry, and is led by Fresenius SE & Co.KGaA and Fraunhofer IZI as academic co-lead.

Have any questions?  
Just send us a message.

We’d love to hear from you! For questions, collaborations, or more info, reach out via the form or email us at contact@easygen-consortium.eu

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This project has received funding from the Innovative Health Initiative Joint Undertaking (JU) under grant agreement No 101194710. The JU receives support from the European Union’s Horizon Europe research and innovation programme and EFPIA. — Funded by the European Union, the private members, and those contributing partners of the IHI JU. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the aforementioned parties. Neither of the aforementioned parties can be held responsible for them.

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